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Diphenoxylate Hydrochloride and Myasthenia gravis

Result of checking the interaction of drug Diphenoxylate Hydrochloride and disease Myasthenia gravis for safety when used together.

Check result:
Diphenoxylate Hydrochloride <> Myasthenia gravis
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Because antimuscarinic agents have anticholinergic effects, they are contraindicated in patients with myasthenia gravis. Their use may be appropriate to reduce adverse muscarinic effects caused by an anticholinesterase agent.

References:
  • "Product Information. Atropine Sulfate Injection, USP (atropine)." ESI Lederle Generics, Philadelphia, PA.
  • Shutt LE, Bowes JB "Atropine and hyoscine." Anaesthesia 34 (1979): 476-90
Diphenoxylate Hydrochloride

Generic Name: atropine / diphenoxylate

Brand Name: Lomotil, Lonox, Lomocot, Vi-Atro

Synonyms: Atropine and diphenoxylate, Diphenoxylate and Atropine

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