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Dimercaprol and Hepatic dysfunction

Generic Name: dimercaprol
Dosage Forms: n.a.
Other Brand Names: BAL In Oil

Result of checking the interaction of drug Dimercaprol and disease Hepatic dysfunction for safety when used together.

Check result:

Dimercaprol <> Hepatic dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of dimercaprol is contraindicated in patients with impaired hepatic function, except for arsenic- associated jaundice. Dimercaprol, not complexed to heavy metals, is metabolized by the liver to inactive forms in patients with normal hepatic function. Hepatic impairment decreases the metabolism of dimercaprol and can result in elimination of potentially nephrotoxic dimercaprol as well as increased CNS toxicity and hypertension.

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