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Acalabrutinib and Hepatic impairment

Result of checking the interaction of drug Acalabrutinib and disease Hepatic impairment for safety when used together.

Check result:

Acalabrutinib <> Hepatic impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Acalabrutinib is metabolized in the liver. Based on the population pharmacokinetic analysis, no clinically relevant difference was observed in subjects with mild or moderate hepatic impairment. The pharmacokinetic of acalabrutinib has not been evaluated in patients with severe hepatic impairment. Close monitoring of liver function is recommended in these patients.

Acalabrutinib

Generic Name: acalabrutinib

Brand Name: Calquence

Synonyms: n.a.

What is Acalabrutinib?