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Dalbavancin Intravenous and Liver disease

Result of checking the interaction of drug Dalbavancin Intravenous and disease Liver disease for safety when used together.

Check result:

Dalbavancin Intravenous <> Liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Dalbavancin is partially metabolized by the liver. In a study of patients with varying degrees of liver impairment given dalbavancin, the mean systemic exposure (AUC) was unchanged in subjects with mild hepatic impairment (Child-Pugh class A), but decreased 28% and 31% in subjects with moderate and severe hepatic impairment (Child-Pugh class B and C), respectively, compared to subjects with normal hepatic function. The clinical significance of these changes is unknown. Therapy with dalbavancin should be administered cautiously in patients with moderate or severe hepatic impairment, as no data are available to determine the appropriate dosing in these patients.

Dalbavancin Intravenous

Generic Name: dalbavancin

Brand Name: Dalvance

Synonyms: Dalbavancin

What is Dalbavancin Intravenous?