Cytovene and Renal dysfunction
Result of checking the interaction of drug Cytovene and disease Renal dysfunction for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Ganciclovir is primarily eliminated by the kidney. Patients with renal impairment may be at greater risk for toxicity from ganciclovir due to decreased drug clearance. Therapy with ganciclovir should be administered cautiously in these patients at reduced dosages. Serum creatinine values should be monitored frequently, and the dosing further adjusted or discontinued accordingly.
- Lake KD, Fletcher CV, Love KR, et al "Ganciclovir pharmacokinetics during renal impairment." Antimicrob Agents Chemother 32 (1988): 1899-900
- Sommadossi JP, Bevan R, Ling T, et al "Clinical pharmacokinetics of ganciclovir in patients with normal and impaired renal function." Rev Infect Dis 10 (1988): s507-14
- "Product Information. Cytovene (ganciclovir)." Genentech, South San Francisco, CA.
Generic Name: ganciclovir
Brand Name: Cytovene
Synonyms: Cytovene (injection), Cytovene-IV