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Cytadren and Adrenal insufficiency
Result of checking the interaction of drug Cytadren and disease Adrenal insufficiency for safety when used together.
Check result:
Cytadren <> Adrenal insufficiency
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Aminoglutethimide suppresses adrenal function and is indicated for the treatment of selected cases of Cushing's syndrome. It generally should not be used in patients with adrenocortical insufficiency.
References:
- Box M, Saltissi D, Fawcett D "Inappropriate secretion of antidiuretic hormone following aminoglutethimide therapy." Br J Urol 58 (1986): 724-5
- Bork E, Hansen M "Severe hyponatremia following simultaneous administration of aminoglutethimide and diuretics." Cancer Treat Rep 70 (1986): 689-90
- Bonneterre J, Nguyen M, Hecquet B, Cappelaere P "Aminoglutethimide-induced hypercholesterolaemia ." Lancet 1 (1984): 912-3
- Davies JP, Bentley P, Ghose RR "Aminoglutethimide-induced hyperkalaemia." Br J Clin Pract 43 (1989): 263-4
- Santen RJ, Misbin RI "Aminoglutethimide: review of pharmacology and clinical use." Pharmacotherapy 1 (1981): 95-120
- "Product Information. Cytadren (aminoglutethimide)." Ciba Self-Medication Inc, Woodbridge, NJ.
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