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Crizotinib and Visual loss

Result of checking the interaction of drug Crizotinib and disease Visual loss for safety when used together.

Check result:
Crizotinib <> Visual loss
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Cases of optic atrophy and optic nerve disorder leading to vision loss have been reported with the use of crizotinib. It is recommended to perform an ophthalmological evaluation consisting of best corrected visual acuity, retinal photographs, visual fields, optical coherence tomography (OCT) and other evaluations as appropriate for new onset of severe visual loss. Discontinue crizotinib in patients with new onset of severe visual loss. There is insufficient information to characterize the risks of resumption of crizotinib in patients with a severe visual loss; a decision to resume treatment with crizotinib should consider the potential benefits to the patient. Care should be exercised when prescribing crizotinib in these patients.

Crizotinib

Generic Name: crizotinib

Brand Name: Xalkori

Synonyms: n.a.

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