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Cotellic and Rhabdomyolysis

Result of checking the interaction of drug Cotellic and disease Rhabdomyolysis for safety when used together.

Check result:

Cotellic <> Rhabdomyolysis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Rhabdomyolysis can occur with the use of cobimetinib. It is recommended to obtain baseline serum creatine phosphokinase (CPK) and creatinine levels prior to initiating therapy with cobimetinib and periodically during treatment as clinically indicated. If CPK is elevated, evaluate for signs and symptoms of rhabdomyolysis or other causes. Depending on the severity of symptoms or CPK elevation, dose interruption or discontinuation may be required. Care should be taken when using this agent in patients at risk for rhabdomyolysis.

Cotellic

Generic Name: cobimetinib

Brand Name: Cotellic

Synonyms: n.a.

What is Cotellic?