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Cosyntropin and GI perforation

Result of checking the interaction of drug Cosyntropin and disease GI perforation for safety when used together.

Check result:

Cosyntropin <> GI perforation

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Adrenocorticotropic agents may cause gastrointestinal perforation and hemorrhage, usually when given in high dosages or for prolonged periods. They may also mask symptoms of complications such as peritonitis or intraabdominal sepsis. Therapy with adrenocorticotropic agents should be administered cautiously in patients with diverticulitis, nonspecific ulcerative colitis (if there is a probability of impending perforation, abscess, or other pyogenic infection), or recent intestinal anastomoses.

References:

"Product Information. Acthrel (corticorelin)." Ferring Laboratories Inc, Tarrytown, NY.
"Product Information. Acthar (corticotropin)." Rhone-Poulenc Rorer, Collegeville, PA.
"Product Information. Cortrosyn (cosyntropin)" Organon, West Orange, NJ.

Cosyntropin

Generic Name: cosyntropin

Brand Name: Cortrosyn

Synonyms: n.a.

What is Cosyntropin?