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Cladribine Tablets and Hepatic dysfunction

Result of checking the interaction of drug Cladribine Tablets and disease Hepatic dysfunction for safety when used together.

Check result:

Cladribine Tablets <> Hepatic dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The pharmacokinetic disposition of cladribine has not be fully assessed. The effect of hepatic impairment on the elimination of cladribine is not known. Therapy with cladribine should be administered cautiously in patient with existing or predisposition to compromised hepatic function. Clinical monitoring of hepatic function is recommended.

References:

"Product Information. Leustatin (cladribine)." Ortho Biotech Inc, Raritan, NJ.
Bryson HM, Sorkin EM "Cladribine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in haematological malignancies." Drugs 46 (1993): 872-94

Cladribine Tablets

Generic Name: cladribine

Brand Name: Mavenclad, Leustatin

Synonyms: Cladribine

What is Cladribine Tablets?