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Carvedilol Extended-Release Capsules and Peripheral vascular disease

Result of checking the interaction of drug Carvedilol Extended-Release Capsules and disease Peripheral vascular disease for safety when used together.

Check result:

Carvedilol Extended-Release Capsules <> Peripheral vascular disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The beta-adrenergic receptor blocking effects of carvedilol may precipitate or aggravate symptoms of arterial insufficiency in patients with peripheral vascular disease. Carvedilol may also attenuate catecholamine-mediated vasodilation during exercise by blocking beta-2 receptors in peripheral vessels. Therapy with carvedilol should be administered cautiously in patients with peripheral vascular disease. Close monitoring for progression of arterial obstruction is advised.

References:

Eliasson K, Lins L-E, Sundqvist K "Peripheral vasospasm during beta-receptor blockade: a comparison between metoprolol and pindolol." Acta Med Scand 665 (1982): 109-12
Eliasson K, Danielson M, Hylander B, Lindblad LE "Raynaud's phenomenon caused by beta-receptor blocking drugs." Acta Med Scand 215 (1984): 333-9
Meyer-Sabellek W, Agrawal B "Antihypertensive profile of carvedilol." Clin Investig 70 Suppl 1 (1992): s43-52
Mashford ML, Coventry D, Hecker R, et al. "Adverse Drug Reactions Advisory Committee: ADRAC report for 1980." Med J Aust 1 (1982): 416-9
Lepantalo M "Beta blockade and intermittent claudication." Acta Med Scand 700 (1985): 1-48
"Product Information. Coreg (carvedilol)." SmithKline Beecham, Philadelphia, PA.
Breckenridge A, Roberts DH "Antihypertensive treatment in concomitant peripheral vascular disease: current experience and the potential of carvedilol." J Cardiovasc Pharmacol 18 Suppl 4 (1991): s78-81

Carvedilol Extended-Release Capsules

Generic Name: carvedilol

Brand Name: Coreg, Coreg CR

Synonyms: Carvedilol

What is Carvedilol Extended-Release Capsules?