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Carfilzomib Intravenous and Cardiac disease

Result of checking the interaction of drug Carfilzomib Intravenous and disease Cardiac disease for safety when used together.

Check result:
Carfilzomib Intravenous <> Cardiac disease
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Carfilzomib can cause new onset or worsening of preexisting cardiac failure, restrictive cardiomyopathy, myocardial ischemia, and myocardial infarction. Patients with preexisting heart problems might be at a greater risk of cardiac toxicity. It is recommended to monitor patients for clinical signs or symptoms of cardiac failure or cardiac ischemia. Evaluate promptly if cardiac toxicity is suspected. Withhold therapy for Grade 3 or 4 cardiac adverse events until recovery, and consider whether to restart at 1 dose level reduction based on a benefit/risk assessment.

Carfilzomib Intravenous

Generic Name: carfilzomib

Brand Name: Kyprolis

Synonyms: Carfilzomib

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