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Caprelsa and QT prolongation

Result of checking the interaction of drug Caprelsa and disease QT prolongation for safety when used together.

Check result:

Caprelsa <> QT prolongation

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Vandetanib can prolong the QT interval, and its use is contraindicated in patients with congenital long QT syndrome. Additionally, vandetanib should not be used in patients with hypocalcemia, hypokalemia, hypomagnesemia, or long QT syndrome. Care should be exercised when using this agent in patients with ventricular arrhythmias or recent myocardial infarction. It is recommended to correct hypocalcemia, hypokalemia and/or hypomagnesemia prior to starting therapy with vandetanib. Obtain an ECG and serum potassium, calcium, magnesium and TSH at baseline, during treatment, and frequently as necessary.

Caprelsa

Generic Name: vandetanib

Brand Name: Caprelsa

Synonyms: n.a.

What is Caprelsa?