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Camphor, lidocaine, and methyl salicylate topical and Renal dysfunction

Result of checking the interaction of drug Camphor, lidocaine, and methyl salicylate topical and disease Renal dysfunction for safety when used together.

Check result:

Camphor, lidocaine, and methyl salicylate topical <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Lidocaine topical is absorbed through intact skin and mucosal membranes. Prolonged exposure, large doses, and/or application to compromised skin or mucosa can result in elevated plasma concentrations of lidocaine. Lidocaine is primarily eliminated by the kidney. Less than 10% is eliminated unchanged in the urine. Two active metabolites (MEGX and GX) have been identified that exhibit antiarrhythmic and convulsant properties. Serum concentrations of lidocaine and the active metabolites are increased and the half-life prolonged in patients with renal impairment. Therapy with lidocaine topical should be administered cautiously and dosing modified for repeated doses in patients with compromised renal function.

Camphor, lidocaine, and methyl salicylate topical

Generic Name: camphor / lidocaine / methyl salicylate topical

Brand Name: JointFlex, Original Ointment, Viva

Synonyms: Camphor, lidocaine, and methyl salicylate (topical)

What is Camphor, lidocaine, and methyl salicylate topical?