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Brimonidine and brinzolamide ophthalmic and Renal/liver

Result of checking the interaction of drug Brimonidine and brinzolamide ophthalmic and disease Renal/liver for safety when used together.

Check result:

Brimonidine and brinzolamide ophthalmic <> Renal/liver

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Topically applied alpha-2 adrenergic receptor agonists are systemically absorbed, with the potential for producing rare but clinically significant systemic effects. There are limited data concerning the pharmacokinetic disposition or the clinical use of these drugs in patients with renal and/or liver disease. Therapy with ophthalmic alpha-2 adrenergic agents should be administered cautiously in patients with significantly impaired renal or hepatic function.

References:

"Product Information. Iopidine (apraclonidine)." Alcon Laboratories Inc, Fort Worth, TX.
"Product Information. Alphagan (brimonidine ophthalmic)." Allergan Inc, Irvine, CA.

Brimonidine and brinzolamide ophthalmic

Generic Name: brimonidine / brinzolamide ophthalmic

Brand Name: Simbrinza

Synonyms: Brinzolamide and Brimonidine

What is Brimonidine and brinzolamide ophthalmic?