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Baricitinib and Infections

Result of checking the interaction of drug Baricitinib and disease Infections for safety when used together.

Check result:
Baricitinib <> Infections
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Serious and sometimes fatal infections due to bacterial, mycobacterial, invasive fungal, viral, or other opportunistic pathogens have been reported in patients receiving baricitinib. The most common serious infections reported included pneumonia, herpes zoster, and urinary tract infection. Avoid use of baricitinib in patients with an active, serious infection, including localized infections. Consider the risks and benefits of treatment prior to initiating baricitinib in these patients. It is recommended to interrupt treatment if a patient develops a serious infection, an opportunistic infection, or sepsis. A patient who develops a new infection during treatment with baricitinib should undergo prompt and complete diagnostic testing appropriate for an immunocompromised patient. Initiate appropriate antimicrobial therapy, monitor closely and interrupt treatment if the patient is not responding to therapy. Do not resume baricitinib until the infection is controlled. Closely monitor patients for the development of signs and symptoms of infection during and after treatment.

Baricitinib

Generic Name: baricitinib

Brand Name: Olumiant

Synonyms: n.a.

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