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Zosyn in Galaxy Containers and Sodium/potassium

Result of checking the interaction of drug Zosyn in Galaxy Containers and disease Sodium/potassium for safety when used together.

Check result:

Zosyn in Galaxy Containers <> Sodium/potassium

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Parenteral piperacillin sodium contains approximately 43 mg (1.85 mEq) of sodium per each gram of piperacillin activity. The combination, piperacillin-tazobactam, contains approximately 54 mg (2.35 mEq) of sodium per gram of piperacillin, or 108 mg (4.7 mEq) per 2.25 gram of total drug. The sodium content should be considered in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension, and fluid retention. In addition, hypokalemia has been reported rarely during therapy with piperacillin and other extended-spectrum penicillin antibiotics, which may be particularly important to bear in mind when treating patients with low potassium reserves or fluid and electrolyte imbalance. Clinical monitoring of electrolytes is recommended if these agents are used for prolonged periods.

References:

"Product Information. Zosyn (piperacillin-tazobactam)." Lederle Laboratories, Wayne, NJ.
Nanji AA, Lindsay J "Ticarcillin associated hypokalemia." Clin Biochem 15 (1982): 118-9
"Product Information. Ticar (ticarcillin)." SmithKline Beecham, Philadelphia, PA.

Zosyn in Galaxy Containers

Generic Name: piperacillin / tazobactam

Brand Name: Zosyn

Synonyms: Zosyn

What is Zosyn in Galaxy Containers?