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Yodoxin and Visual field defects

Result of checking the interaction of drug Yodoxin and disease Visual field defects for safety when used together.

Check result:

Yodoxin <> Visual field defects

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of iodoquinol has been associated with optic neuritis and optic atrophy when given in high dosages for prolonged periods. Optic atrophy has been reported mostly in children treated for acrodermatitis enteropathica at daily dosages between 1300 to 3600 mg for up to two years. Visual deterioration may be irreversible. Therapy with iodoquinol should be administered cautiously in patients with or predisposed to visual defects. Some clinicians also recommend not using iodoquinol and related agents in pediatric patients under 12 years of age. Long-term therapy should be avoided in all patients.

References:

Oakley GP Jr "The neurotoxicity of the halogenated hydroxyquinolines. A commentary." JAMA 225 (1973): 395-7
Fleisher DI, Hepler RS, Landau JW "Blindness during diiodohydroxyquin (Diodoquin) therapy: a case report." Pediatrics 54 (1974): 106-8
Idriss ZH "Letter: Diiodohydroxyquin and optic atrophy." Pediatrics 55 (1975): 299
"Product Information. Yodoxin (iodoquinol)." Glenwood Inc, Tenafly, NJ.
Committee on Drugs "Blindness and neuropathy from diiodohydroxyquin-like drugs." Pediatrics 54 (1974): 378-9
Pittman FE, Westphal MC "Optic atrophy following treatment with diiodohydroxyquin." Pediatrics 54 (1974): 81-3
American Academy of Pediatrics Committtee on Drugs "Clioquinol (iodochlorhydroxyquin, vioform) and iodoquinol (diiodohydroxyquin): blindness and neuropathy." Pediatrics 86 (1990): 797-8
Behrens MM "Letter: Optic atrophy in children after diiodohydroxyquin therapy." JAMA 228 (1974): 693-4

Yodoxin

Generic Name: iodoquinol

Brand Name:

Synonyms: Yodoxin (Oral)

What is Yodoxin?