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Vinorelbine Tartrate and Myelosuppression

Generic Name: vinorelbine
Dosage Forms: n.a.
Other Brand Names: Navelbine

Result of checking the interaction of drug Vinorelbine Tartrate and disease Myelosuppression for safety when used together.

Check result:

Vinorelbine Tartrate <> Myelosuppression

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of vinorelbine is contraindicated in patients with neutrophil counts < 1000/mm3. Vinorelbine induces dose-dependent myelosuppression, primarily neutropenia. Therapy with vinorelbine should be administered with extreme caution and dosage modification considered in patients whose bone marrow reserve may be depressed by prior chemotherapy or irradiation or whose marrow function is recovering from previous cytotoxic therapy. Patients should be instructed to immediately report any signs or symptoms suggesting bone marrow suppression such as fever, sore throat, local infection, or bleeding. Close clinical monitoring of hematopoietic function is recommended.

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