Drug search by name

Velban and Pulmonary dysfunction

Result of checking the interaction of drug Velban and disease Pulmonary dysfunction for safety when used together.

Check result:

Velban <> Pulmonary dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Acute shortness of breath and bronchospasm, some severe and life-threatening, have been reported with the use of vinca alkaloids. These reactions were observed most often during combination therapy with mitomycin C, occurring within minutes to several hours after administration of the vinca alkaloid or up to 2 weeks following the mitomycin dose. Therapy with vinca alkaloids should be administered cautiously in patients with preexisting pulmonary dysfunction. Aggressive treatment may be necessary, including use of supplemental oxygen, bronchodilators, and/or corticosteroids. In patients who develop progressive dyspnea requiring chronic therapy, vinca alkaloid should not be readministered.

References:

"Product Information. Navelbine (vinorelbine)." Glaxo Wellcome, Research Triangle Pk, NC.
"Product Information. Oncovin (vincristine)." Lilly, Eli and Company, Indianapolis, IN.
"Product Information. Velban (vinblastine)." Lilly, Eli and Company, Indianapolis, IN.

Velban

Generic Name: vinblastine

Brand Name: Velban

Synonyms: n.a.

What is Velban?