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Varubi and Renal impairment
Result of checking the interaction of drug Varubi and disease Renal impairment for safety when used together.
Check result:
Varubi <> Renal impairment
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Population pharmacokinetic analyses suggest that no dose adjustment of rolapitant is required in patients with mild or moderate renal impairment. The effect of severe renal impairment on the pharmacokinetics of rolapitant is unknown to determine a dose. This agent has not been studied in patients with end-stage renal disease requiring hemodialysis. Caution is recommended.
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