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Unoprostone and Renal/liver disease

Result of checking the interaction of drug Unoprostone and disease Renal/liver disease for safety when used together.

Check result:
Unoprostone <> Renal/liver disease
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Unoprostone isopropyl is hydrolyzed by esterases in the cornea and conjunctival epithelium to the active free acid form, which is absorbed systemically and metabolized by the liver. The metabolites are eliminated by the kidney. Unoprostone isopropyl has not been adequately studied in the treatment of patients with impaired renal and/or hepatic function. Therapy with unoprostone isopropyl ophthalmic solution should be administered cautiously in such patients.

References:
  • "Product Information. Rescula (unoprostone ophthalmic)" Ciba Vision Ophthalmics, Duluth, GA.
Unoprostone

Generic Name: unoprostone ophthalmic

Brand Name: Rescula

Synonyms: n.a.

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