Tepadina Injection and Hepatic dysfunction
Result of checking the interaction of drug Tepadina Injection and disease Hepatic dysfunction for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Thiotepa is rapidly metabolized by the liver to a biologically active form. The pharmacokinetic disposition of thiotepa has not be evaluated in patients with hepatic dysfunction. The use of thiotepa may be contraindicated in patients with existing hepatic damage. If the need outweighs the risk, extreme caution should be exercised in administering thiotepa and therapy should be initiated at a reduced dosage. Clinical monitoring of hepatic function is recommended.
- "Product Information. Thiotepa (thiotepa)." Hikma USA (formerly West-Ward Pharmaceutical Corporation), Eatontown, NJ.
Generic Name: thiotepa
Brand Name: Tepadina, Thioplex
Synonyms: Tepadina