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Tadalafil Tablets (Pulmonary Hypertension) and Liver disease

Result of checking the interaction of drug Tadalafil Tablets (Pulmonary Hypertension) and disease Liver disease for safety when used together.

Check result:

Tadalafil Tablets (Pulmonary Hypertension) <> Liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Phosphodiesterase 5 (PDE-5) inhibitors are cleared predominantly by hepatic metabolism. The pharmacokinetic disposition of these agents has not been assessed in patients with severe hepatic impairment. No dosage modification is recommended for patients with mild to moderate hepatic impairment, however, therapy with these agents should not be administered to patients with severe hepatic impairment. In patients with mild hepatic impairment a lower dose of these agents should be used as initial therapy.

Tadalafil Tablets (Pulmonary Hypertension)

Generic Name: tadalafil

Brand Name: Adcirca, Cialis, Alyq

Synonyms: Tadalafil

What is Tadalafil Tablets (Pulmonary Hypertension)?