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Suprep Bowel Prep Kit and Cardiac disease

Result of checking the interaction of drug Suprep Bowel Prep Kit and disease Cardiac disease for safety when used together.

Check result:
Suprep Bowel Prep Kit <> Cardiac disease
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The parenteral administration of magnesium is contraindicated in patients with heart block or heart damage from myocardial infarction. These conditions may be exacerbated during magnesium infusion. High serum levels of magnesium (> 4.5 mEq/L) can cause sinus bradycardia, AV block, nodal rhythms, and bundle branch block, which can progress to asystole and cardiac arrest at magnesium levels of approximately 14 mEq/L to 15 mEq/L. If parenteral magnesium is used in patients with preexisting conduction disturbances, it should be infused at a slower rate, and cardiac function and serum magnesium level should be closely monitored. The usual precautionary measures should be observed to prevent hypermagnesemia, and IV calcium salts (e.g., calcium gluconate), pressors, cardiac pacemakers, and equipment for supportive care should be immediately available in case of acute magnesium intoxication.

References:
  • "Product Information. Magnesium Sulfate (magnesium sulfate)." Abbott Pharmaceutical, Abbott Park, IL.
  • Sherer DM, Cialone PR, Abramowicz JS, Woods JR Jr "Transient symptomatic subendocardial ischemia during intravenous magnesium sulfate tocolytic therapy." Am J Obstet Gynecol 166 (1992): 33-5
  • Viskin S, Belhassen B, Laniado S "Deterioration of ventricular tachycardia to ventricular fibrillation after rapid intravenous administration of magnesium sulfate." Chest 101 (1992): 1445-7
Suprep Bowel Prep Kit

Generic Name: magnesium sulfate / potassium sulfate / sodium sulfate

Brand Name: Suprep Bowel Prep Kit

Synonyms: Suprep Bowel Prep

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