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Sonata and Renal dysfunction

Result of checking the interaction of drug Sonata and disease Renal dysfunction for safety when used together.

Check result:

Sonata <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Zaleplon is excreted in the urine almost exclusively as metabolites and their glucuronides. The pharmacokinetics of zaleplon are not altered in patients with renal insufficiency. According to the manufacturer, dosage adjustments are not necessary in patients with mild to moderate renal impairment. However, caution may be appropriate if the drug is used in patients with severe renal impairment, since data establishing its safety and efficacy are lacking in such patients.

References:

Dooley M, Plosker GL "Zaleplon - A review of its use in the treatment of insomnia." Drugs 60 (2000): 413-45
"Product Information. Sonata (zaleplon)" Wyeth-Ayerst Laboratories, Philadelphia, PA.

Sonata

Generic Name: zaleplon

Brand Name: Sonata

Synonyms: n.a.

What is Sonata?