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Salagen and GI/bladder neck obstruction

Result of checking the interaction of drug Salagen and disease GI/bladder neck obstruction for safety when used together.

Check result:

Salagen <> GI/bladder neck obstruction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of cholinergic agonists is contraindicated in patients with peptic ulcers, mechanical GI obstruction, acute GI inflammatory conditions, or urinary obstruction. Cholinergic activity may result in an increase in gastric acid secretion, GI motility, and gastric contractions. In patients with urinary retention, urinary reflux may occur if the sphincter fails to relax when the bladder is contracted by cholinergic stimulation. The reflux of urine from the bladder can cause infection in the kidneys and upper urinary tract if bacteriuria is present.

References:

"Product Information. Salagen Tablets (pilocarpine)." Boehringer-Ingelheim, Ridgefield, CT.
"Product Information. Urecholine (bethanechol)." Merck & Co, Inc, West Point, PA.

Salagen

Generic Name: pilocarpine

Brand Name: Salagen

Synonyms: n.a.

What is Salagen?