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Rythmol SR and Renal dysfunction

Result of checking the interaction of drug Rythmol SR and disease Renal dysfunction for safety when used together.

Check result:

Rythmol SR <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Propafenone is partially eliminated by the kidney and approximately 50% of its metabolites are excreted in the urine. Therapy with propafenone should be administered cautiously in patients with renal impairment, monitoring for signs of overdosage.

References:

"Product Information. Rhythmol (propafenone)." Knoll Pharmaceutical Company, Whippany, NJ.
Burgess ED, Duff HJ "Hemodialysis removal of propafenone." Pharmacotherapy 9 (1989): 331-3
Burgess E, Duff H, Wilkes P "Propafenone disposition in renal insufficiency and renal failure." J Clin Pharmacol 29 (1989): 112-3
Chan GL, Axelson JE, Price JD, et al "In vitro protein binding of propafenone in normal and uraemic human sera." Eur J Clin Pharmacol 36 (1989): 495-9

Rythmol SR

Generic Name: propafenone

Brand Name: Rythmol, Rythmol SR

Synonyms: Rythmol Extended Release

What is Rythmol SR?