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Rubraca and Hepatic impairment
Result of checking the interaction of drug Rubraca and disease Hepatic impairment for safety when used together.
Check result:
Rubraca <> Hepatic impairment
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Based on population pharmacokinetic analyses no dose adjustment is recommended for patients with mild hepatic impairment. Caution should be exercised when using this agent in patients with moderate to severe hepatic impairment as the pharmacokinetics of rucaparib in these patients are unknown.
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