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Roflumilast Tablets and Hepatic impairment

Result of checking the interaction of drug Roflumilast Tablets and disease Hepatic impairment for safety when used together.

Check result:

Roflumilast Tablets <> Hepatic impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Roflumilast is contraindicated in patients with moderate to severe liver impairment (Child-Pugh B or C). Roflumilast is extensively metabolized via Phase I (cytochrome P450) and Phase II (conjugation) reactions. Clinicians should consider the risk-benefit of administering roflumilast to patients with mild liver impairment (Child-Pugh A).

Roflumilast Tablets

Generic Name: roflumilast

Brand Name: Daliresp

Synonyms: Roflumilast

What is Roflumilast Tablets?