Rifampin, Isoniazid, and Pyrazinamide and Porphyria
Result of checking the interaction of drug Rifampin, Isoniazid, and Pyrazinamide and disease Porphyria for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Rifampin may induce the activity of delta amino levulinic acid synthetase, an enzyme involved in the biosynthesis of porphyrins. The use of rifampin has been associated with isolated cases of porphyria exacerbation. Therapy with rifampin should be administered cautiously in patients with a history of porphyria.
- "Product Information. Rifadin (rifampin)." Hoechst Marion-Roussel Inc, Kansas City, MO.
Generic Name: isoniazid / pyrazinamide / rifampin
Brand Name: Rifater
Synonyms: Isoniazid, pyrazinamide, and rifampin