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Rifabutin and TB

Result of checking the interaction of drug Rifabutin and disease TB for safety when used together.

Check result:
Rifabutin <> TB
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Rifabutin should not be given as monotherapy in patients with active tuberculosis (TB). The administration of rifabutin in the absence of appropriate antituberculous agents may induce organisms resistant to rifabutin and other rifamycins, including rifampin and rifapentine. Likewise, patients must not have active TB when receiving rifabutin therapy for Mycobacterium avium complex prophylaxis or other indications where rifabutin might be used alone. Patients who develop symptoms consistent with active TB during rifabutin therapy should be evaluated promptly so that an effective antituberculosis regimen may be instituted if necessary.

References:
  • "Product Information. Mycobutin (rifabutin)." Pharmacia and Upjohn, Kalamazoo, MI.
Rifabutin

Generic Name: rifabutin

Brand Name: Mycobutin

Synonyms: n.a.

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