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Ribavirin (Oral Inhalation) and Mechanical ventilation

Result of checking the interaction of drug Ribavirin (Oral Inhalation) and disease Mechanical ventilation for safety when used together.

Check result:

Ribavirin (Oral Inhalation) <> Mechanical ventilation

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of aerosolized ribavirin in patients requiring mechanical ventilation demands meticulous care by a trained staff in order to prevent complications associated with drug precipitation within the respiratory equipment. Close, continuous monitoring, as well as frequent cleaning and changes of line valves and ventilator tubings and filters, are conducive to favorable outcomes. Certain equipment implementations and settings are also essential, but specific details regarding equipment circuitry maintenance and modifications are beyond the scope of this application and should be obtained from the SPAG-2 Operator's Manual.

References:

Rodriguez WJ, Parrott RH "Ribavirin aerosol treatment of serious respiratory syncytial virus infection in infants." Infect Dis Clin North Am 1 (1987): 425-39
"Product Information. Virazole (ribavirin)." ICN Pharmaceuticals Inc, Cost Mesa, CA.
Janai HK, Marks MI, Zaleska M, Stutman HR "Ribavirin: adverse drug reactions, 1986 to 1988." Pediatr Infect Dis J 9 (1990): 209-11
Meert KL, Sarnaik AP, Gelmini MJ, Lieh-Lai MW "Aerosolized ribavirin in mechanically ventilated children with respiratory syncytial virus lower respiratory tract disease: a prospective, double-blind, randomized trial." Crit Care Med 22 (1994): 566-72

Ribavirin (Oral Inhalation)

Generic Name: ribavirin

Brand Name: Rebetol, RibaPak, Ribasphere, RibaTab, Virazole, Copegus, RibaPak 600, Moderiba, Moderiba 800 Dose Pack, Moderiba 1200 Dose Pack, Moderiba 1000 Dose Pack, Moderiba 600 Dose Pack

Synonyms: Ribavirin

What is Ribavirin (Oral Inhalation)?