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Ranolazine and Severe hepatic impairment

Result of checking the interaction of drug Ranolazine and disease Severe hepatic impairment for safety when used together.

Check result:
Ranolazine <> Severe hepatic impairment
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Plasma concentrations of ranolazine increased by 30% in patients with mild (Child-Pugh Class A), and by 60% in patients with moderate (Child-Pugh B) hepatic impairment. The use of ranolazine is contraindicated in patients with clinically significant hepatic impairment.

Ranolazine

Generic Name: ranolazine

Brand Name: Ranexa

Synonyms: n.a.

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