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Quinja and Visual field defects

Result of checking the interaction of drug Quinja and disease Visual field defects for safety when used together.

Check result:

Quinja <> Visual field defects

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Percutaneous absorption of iodoquinol topical has not been characterized. However, other 8-hydroxyquinoline derivatives (clioquinol, chlorquinaldol) are systemically absorbed following topical application. The following visual field defects have occurred during oral iodoquinol therapy: optic neuritis and optic atrophy when given in high dosages for prolonged periods. Optic atrophy has been reported mostly in children treated for acrodermatitis enteropathica at daily dosages between 1300 to 3600 mg for up to two years. Visual deterioration may be irreversible. Therapy with iodoquinol should be administered cautiously in patients with or predisposed to visual defects. Some clinicians also recommend not using iodoquinol and related agents in pediatric patients under 12 years of age. Long-term therapy should be avoided in all patients.

References:

Oakley GP Jr "The neurotoxicity of the halogenated hydroxyquinolines. A commentary." JAMA 225 (1973): 395-7
"Product Information. Yodoxin (iodoquinol)." Glenwood Inc, Tenafly, NJ.
Fleisher DI, Hepler RS, Landau JW "Blindness during diiodohydroxyquin (Diodoquin) therapy: a case report." Pediatrics 54 (1974): 106-8
Behrens MM "Letter: Optic atrophy in children after diiodohydroxyquin therapy." JAMA 228 (1974): 693-4
Idriss ZH "Letter: Diiodohydroxyquin and optic atrophy." Pediatrics 55 (1975): 299
Pittman FE, Westphal MC "Optic atrophy following treatment with diiodohydroxyquin." Pediatrics 54 (1974): 81-3

Quinja

Generic Name: aloe polysaccharides / iodoquinol topical

Brand Name: Aloquin, Quinja, Iodopen

Synonyms: n.a.

What is Quinja?