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Protopam Chloride and Renal dysfunction

Generic Name: pralidoxime
Dosage Forms: injection, powder, lyophilized, for solution
Other Brand Names: Protopam Chloride

Result of checking the interaction of drug Protopam Chloride and disease Renal dysfunction for safety when used together.

Check result:

Protopam Chloride <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Pralidoxime is eliminated by the kidney. Approximately 80% to 90% of pralidoxime is excreted in the urine as unchanged drug. The serum concentration of pralidoxime is increased in patients with renal impairment. Therapy with pralidoxime should be administered cautiously and dosages reduced in patients with compromised renal function. Clinical monitoring of renal function and muscular activity is recommended.

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