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Prothrombin Complex Conc (Human) [(Factors II, VII, IX, X), Prot C, Prot S] and Thromboembolic complications

Result of checking the interaction of drug Prothrombin Complex Conc (Human) [(Factors II, VII, IX, X), Prot C, Prot S] and disease Thromboembolic complications for safety when used together.

Check result:

Prothrombin Complex Conc (Human) [(Factors II, VII, IX, X), Prot C, Prot S] <> Thromboembolic complications

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Both fatal and non-fatal arterial thromboembolic events, venous thromboembolic events and disseminated intravascular coagulation have been reported with the use of prothrombin complex. Patients being treated with Vitamin K antagonists have underlying disease states that may predispose them to thromboembolic events, as those with a history of a prior thromboembolism. Reversing, exposes patients to the thromboembolic risk of their underlying disease. Resumption of anticoagulation should be carefully examined following administration of prothrombin complex and Vitamin K once the risk of thromboembolic events outweighs the risk of bleeding. It is recommended to monitor patients undergoing prothrombin complex therapy for signs and symptoms of thromboembolic events during and after the administration of treatment. The use of prothrombin complex may not be suitable for patients with thromboembolic events in the prior three months.

Prothrombin Complex Conc (Human) [(Factors II, VII, IX, X), Prot C, Prot S]

Generic Name: prothrombin complex

Brand Name: Kcentra

Synonyms: Prothrombin Complex Concentrate (Human) [(Factors II, VII, IX, X), Protein C, and Protein S]

What is Prothrombin Complex Conc (Human) [(Factors II, VII, IX, X), Prot C, Prot S]?