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Propafenone Extended Release Capsule and Cardiac dysfunction

Result of checking the interaction of drug Propafenone Extended Release Capsule and disease Cardiac dysfunction for safety when used together.

Check result:

Propafenone Extended Release Capsule <> Cardiac dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of propafenone is contraindicated in patients with uncontrolled congestive heart failure, cardiogenic shock, bradycardia, or marked hypotension. Propafenone can exacerbate congestive heart failure by beta blockade of sympathetic stimulation necessary for circulatory support. Propafenone also has negative inotropic activity that can depress cardiac output and cardiac index.

References:

Ravid S, Podrid PJ, Lampert S, Lown B "Congestive heart failure induced by six of the newer antiarrhythmic drugs." J Am Coll Cardiol 14 (1989): 1326-30
"Product Information. Rhythmol (propafenone)." Knoll Pharmaceutical Company, Whippany, NJ.

Propafenone Extended Release Capsule

Generic Name: propafenone

Brand Name: Rythmol, Rythmol SR

Synonyms: Propafenone

What is Propafenone Extended Release Capsule?