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Procainamide and Anticholinergic activity

Result of checking the interaction of drug Procainamide and disease Anticholinergic activity for safety when used together.

Check result:

Procainamide <> Anticholinergic activity

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Procainamide decreases the release of acetylcholine from skeletal muscle motor nerve endings. Procainamide can worsen the symptoms of myasthenia gravis. Therapy with procainamide should be administered cautiously in patients with myasthenia gravis.

References:

"Product Information. Procan SR (procainamide)." Parke-Davis, Morris Plains, NJ.
Niakan E, Bertorini T, Acchirardo S, Werner M "Procainamide-induced myasthenia-like weakness in a patient with periperal neuropathy." Arch Neurol 38 (1981): 378-9
Miller CD, Oleshansky MA, Gibson KF, Cantilena LR "Procainamide-induced myasthenia-like weakness and dysphagia." Ther Drug Monit 15 (1993): 251-4
"Product Information. Pronestyl (procainamide)." Apothecon Inc, Plainsboro, NJ.

Procainamide

Generic Name: procainamide

Brand Name: Pronestyl, Procan SR, Pronestyl-SR, Procanbid

Synonyms: Procainamide (injection)

What is Procainamide?