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Probenecid and colchicine and Bone marrow suppression
Result of checking the interaction of drug Probenecid and colchicine and disease Bone marrow suppression for safety when used together.
Check result:
Probenecid and colchicine <> Bone marrow suppression
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:The use of colchicine should be used with caution in patients with bone marrow suppression. Patients on long term therapy may require periodic blood counts.
References:
- Wallace SL, Singer JZ, Duncan GJ, Wigley FM, Kuncl RW "Renal function predicts colchicine toxicity: guidelines for the prophylactic use of colchicine in gout." J Rheumatol 18 (1991): 264-9
- Vedia C, Mascort JJ, Carrasco I, Olive A "Colchicine and thrombopenia." Clin Exp Rheumatol 11 (1993): 458
- Finklestein M, Goldman L, Grace ND, Foley M, Randall N "Granulocytopenia complicating colchicine therapy for primary biliary cirrhosis." Gastroenterology 93 (1987): 1231-5
- Ferrannini E, Pentimone F "Marrow aplasia following colchicine treatment for gouty arthritis." Clin Exp Rheumatol 2 (1984): 173-5
- Neuss MN, McCallum RM, Brenckman WD, Silberman HR "Long-term colchicine administration leading to colchicine toxicity and death." Arthritis Rheum 29 (1986): 448-9
- "Product Information. Colchicine (colchicine)." Lilly, Eli and Company, Indianapolis, IN.
- Liu YK, Hymowitz R, Carroll MG "Marrow aplasia induced by colchicine. A case report." Arthritis Rheum 21 (1978): 731-5
- Stanley MW, Taurog JD, Snover DC "Fatal colchicine toxicity: report of a case." Clin Exp Rheumatol 2 (1984): 167-71
Probenecid and colchicine
Generic Name: colchicine / probenecid
Brand Name:
Synonyms: Probenecid and colchicine (Oral)
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