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Primacor and Hypotension

Result of checking the interaction of drug Primacor and disease Hypotension for safety when used together.

Check result:
Primacor <> Hypotension
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of amrinone or milrinone is associated with a fall in blood pressure. Some patients have required correction by intravenous infusion of plasma. Therapy with amrinone or milrinone should be administered cautiously in hypotensive patients. Monitoring fluid and electrolyte status, renal function, blood pressure, and heart rate is recommended.

References:
  • Mancini D, LeJemtel T, Sonnenblick E "Intravenous use of amrinone for the treatment of the failing heart." Am J Cardiol 56 (1985): b8-15
  • Wilsmhurst PT, Webb-Peploe MM "Side effects of amrinone therapy." Br Heart J 49 (1983): 447-51
  • Bottorff MB, Rutledge DR, Pieper JA "Evaluation of intravenous amrinone: the first of a new class of positive inotropic agents with vasodilator properties." Pharmacotherapy 5 (1985): 227-37
  • Burns P, Ondrejicka JS "Criteria for use of amrinone lactate in hospitalized adult patients." Clin Pharm 9 (1990): 882-4
  • Larsson R, Liedholm H, Andersson KE, Keane MA, Henry G "Pharmacokinetics and effects on blood pressure of a single oral dose of milrinone in healthy subjects and in patients with renal impairment." Eur J Clin Pharmacol 29 (1986): 549-53
  • "Product Information. Inocor (inamrinone)." Sanofi Winthrop Pharmaceuticals, New York, NY.
  • Packer M, Carver JR, Rodeheffer RJ, et al "Effect of oral milrinone of mortality in severe chronic heart failure." N Engl J Med 325 (1991): 1468-75
  • Hasegawa R "Milrinone, a new agent for the treatment of congestive heart failure." Clin Pharm 5 (1986): 201-5
Primacor

Generic Name: milrinone

Brand Name: Primacor, Primacor IV.

Synonyms: n.a.

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