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Aranesp (Darbepoetin Alfa Vials) and Hemodialysis

Result of checking the interaction of drug Aranesp (Darbepoetin Alfa Vials) and disease Hemodialysis for safety when used together.

Check result:

Aranesp (Darbepoetin Alfa Vials) <> Hemodialysis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The increase in hematocrit and decrease in plasma volume associated with erythropoiesis-stimulating agents therapy may, theoretically, affect dialysis efficiency. Patients may require adjustments in their dialysis prescription after initiation of erythropoiesis stimulating agents. During hemodialysis, patients may require increased anticoagulation with heparin to prevent clotting.

References:

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Kindler J, Echardt KU, Ehmer B, et al "Single-dose pharmacokinetics of recombinant human erythropoietin in patients with various degrees of renal failure." Nephrol Dial Transplant 4 (1989): 345-9
Swanepoel C, Jacobs P, Byrne MJ, Rayner B, Cassidy MJD, Meyer J "The effect of recombinant human erythropoietin on haematopoiesis in patients undergoing haemodialysis." S Afr Med J 86 (1996): 952-5
Ateshkadi A, Johnson CA, Oxton LL, Hammond TG, Bohenek WS, Zimmerman SW "Pharmacokinetics of intraperitoneal, intravenous, and subcutaneous recombinant human erythropoietin in patients on continuous ambulatory peritoneal dialysis." Am J Kidney Dis 21 (1993): 635-42
MacDougall IC, Neubert P, Coles GA, Roberts DE, Dharmasena AD, Williams JD "Pharmacokinetics of recombinant human erythropoietin in patients on continuous ambulatory peritoneal dialysis." Lancet 02/25/89 (1989): 425-7
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"Product Information. Epogen (epoetin alfa)." Amgen, Thousand Oaks, CA.

Aranesp (Darbepoetin Alfa Vials)

Generic Name: darbepoetin alfa

Brand Name: Aranesp, Aranesp SureClick, Aranesp Albumin Free, Aranesp SingleJect

Synonyms: Aranesp

What is Aranesp (Darbepoetin Alfa Vials)?