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PegIntron and Depression

Result of checking the interaction of drug PegIntron and disease Depression for safety when used together.

Check result:

PegIntron <> Depression

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Interferons (alfa or beta) can induce depression and suicidal behavior. Suicidal attempts and suicides have been reported. Therapy with interferons (alfa or beta) should be administered cautiously to patients with or predisposed to mental depression. Clinical monitoring of psychological status is recommended.

References:

"Product Information. Avonex (interferon beta-1a)." Biogen, Cambridge, MA.
"Product Information. Betaseron (interferon beta-1b)." Berlex, Richmond, CA.
"Product Information. Infergen (interferon alfacon-1)." Amgen, Thousand Oaks, CA.
"Product Information. Intron A (interferon alfa-2b)." Schering Laboratories, Kenilworth, NJ.

PegIntron

Generic Name: peginterferon alfa-2b

Brand Name: PegIntron, Sylatron, PegIntron Redipen

Synonyms: Pegintron

What is PegIntron?

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PegIntron <> Depression

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

Consumer:

Life-threatening or fatal neuropsychiatric reactions have been reported in patients receiving peginterferons alfa, including suicide, suicide ideation, homicidal ideation, depression, relapse of drug addiction, and drug overdose. These reactions have occurred in patients with and without previous psychiatric illness. These drugs should be used with extreme caution in patients with a history of depression. Other events reported include aggressive behavior, psychosis, hallucinations, bipolar disorder and mania. Patients should be monitored for any evidence of depression or other psychiatric symptoms, and they should be advised to report any signs or symptoms of depression or other changes in mood or behavior. In severe cases, therapy should be stopped immediately and psychiatric intervention should be instituted.

PegIntron

Generic Name: peginterferon alfa-2b

Brand Name: PegIntron, Sylatron, PegIntron Redipen

Synonyms: Pegintron

What is PegIntron?

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