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Pegaspargase and Pancreatic dysfunction

Result of checking the interaction of drug Pegaspargase and disease Pancreatic dysfunction for safety when used together.

Check result:
Pegaspargase <> Pancreatic dysfunction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of pegaspargase is contraindicated in patients with or a history of pancreatitis. Pegaspargase can cause decreased insulin synthesis or inflammation and/or necrosis of cells of the pancreas. Fulminant and fatal pancreatitis has occurred. Clinical monitoring of pancreatic function, including serum amylase levels, is recommended.

References:
  • "Product Information. Oncaspar (pegaspargase)." Rhone-Poulenc Rorer, Collegeville, PA.
Pegaspargase

Generic Name: pegaspargase

Brand Name: Oncaspar

Synonyms: n.a.

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