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Apalutamide and Renal impairment
Result of checking the interaction of drug Apalutamide and disease Renal impairment for safety when used together.
Check result:
Apalutamide <> Renal impairment
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:No clinically significant differences in the pharmacokinetics of apalutamide or its major metabolite were observed in patients with mild to moderate renal impairment. The effect on patients with severe renal impairment or end-stage renal disease on apalutamide pharmacokinetics is unknown. Close monitoring of renal function is recommended in these patients.
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