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Pazopanib Hydrochloride and QT prolongation

Result of checking the interaction of drug Pazopanib Hydrochloride and disease QT prolongation for safety when used together.

Check result:

Pazopanib Hydrochloride <> QT prolongation

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Pazopanib can cause QT prolongation which may lead to an increased risk for ventricular arrhythmias, including Torsade de Pointes. This agent should be administered with caution in patients with a history of QT interval prolongation, in patients taking antiarrhythmics or other medications that may prolong QT interval. Serum electrolytes should be corrected before initiating therapy with this agent. Periodic monitoring of ECGs and electrolytes is recommended in these patients.

Pazopanib Hydrochloride

Generic Name: pazopanib

Brand Name: Votrient

Synonyms: Pazopanib

What is Pazopanib Hydrochloride?