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Oxaliplatin Concentrate Injection and Renal impairment

Result of checking the interaction of drug Oxaliplatin Concentrate Injection and disease Renal impairment for safety when used together.

Check result:

Oxaliplatin Concentrate Injection <> Renal impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The major route of platinum elimination is renal excretion. The exposure (AUC) of unbound platinum in plasma ultrafiltrate tends to increase in renally impaired patients. The starting dose of oxaliplatin should be reduced in patients with severe renal impairment (creatinine clearance < 30 mL/min). Caution and close monitoring should be exercised when oxaliplatin is administered to patients with renal impairment.

Oxaliplatin Concentrate Injection

Generic Name: oxaliplatin

Brand Name: Eloxatin

Synonyms: Oxaliplatin

What is Oxaliplatin Concentrate Injection?