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Nuwiq (Antihemophilic Factor (Recombinant) (Helixate FS and Kogenate FS)) and Blood isoagglutinin

Result of checking the interaction of drug Nuwiq (Antihemophilic Factor (Recombinant) (Helixate FS and Kogenate FS)) and disease Blood isoagglutinin for safety when used together.

Check result:

Nuwiq (Antihemophilic Factor (Recombinant) (Helixate FS and Kogenate FS)) <> Blood isoagglutinin

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Blood group isoagglutinins (anti-A and anti-B) are present in antihemophilic factor (human) at concentrations that may not be clinically significant when used to control minor bleeds. Monitoring of hematocrit and Coombs for signs of intravascular hemolysis and falling hematocrit is recommended in patients with blood groups A, B, or AB when large or frequently repeated doses of antihemophilic factor (human) are administered. Acute hemolytic anemia may occur, resulting in increased bleeding tendency or hyperfibrinogenemia. Should this condition occur, leading to progressive hemolytic anemia, discontinue treatment and consider administering serologically compatible Type O red blood cells and providing alternative therapy.

References:

"Product Information. Koate-HP (antihemophilic factor)." Bayer, West Haven, CT.

Nuwiq (Antihemophilic Factor (Recombinant) (Helixate FS and Kogenate FS))

Generic Name: antihemophilic factor

Brand Name: Hemofil-M, Koate-DVI, Monoclate-P, Advate, Adynovate, Afstyla, Eloctate with Fc Fusion Protein, Helixate FS, Kogenate FS, Kovaltry, Novoeight, Nuwiq, Recombinate, Xyntha, Jivi, Obizur

Synonyms: Antihemophilic factor (human), Antihemophilic Factor (Human)

What is Nuwiq (Antihemophilic Factor (Recombinant) (Helixate FS and Kogenate FS))?