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Nitrofurantoin Macrocrystals and Peripheral neuropathy

Result of checking the interaction of drug Nitrofurantoin Macrocrystals and disease Peripheral neuropathy for safety when used together.

Check result:

Nitrofurantoin Macrocrystals <> Peripheral neuropathy

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of nitrofurantoin has occasionally been associated with the development of peripheral neuropathy, which may be severe and irreversible. Patients at risk include the elderly and those with renal impairment, anemia, diabetes mellitus, electrolyte imbalance, vitamin B12 deficiency, diabetes, and/or debilitating diseases. Therapy with nitrofurantoin should be administered cautiously in patients with one or more risk factors and/or preexisting peripheral neuropathy. Periodic monitoring of renal function is recommended during prolonged therapy.

References:

Craven RS "Furadantin neuropathy." Aust N Z J Med 3 (1971): 246-9
White WT, Harrison L, Dumas J "Nitrofurantoin unmasking peripheral neuropathy in a type 2 diabetic patient." Arch Intern Med 144 (1984): 821
Yiannikas C, Pollard JD, McLeod JG "Nitrofurantoin neuropathy." Aust N Z J Med 11 (1981): 400-5

Nitrofurantoin Macrocrystals

Generic Name: nitrofurantoin

Brand Name: Furadantin, Macrobid, Macrodantin, Nitro Macro

Synonyms: Nitrofurantoin

What is Nitrofurantoin Macrocrystals?