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Ninlaro and Renal impairment

Result of checking the interaction of drug Ninlaro and disease Renal impairment for safety when used together.

Check result:

Ninlaro <> Renal impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Population PK analysis in patients with severe renal impairment or ESRD requiring dialysis showed an increase AUC when compared to patients with normal renal function. The pharmacokinetic of ixazomib was similar in patients with normal renal function and in patients with mild or moderate renal impairment. It is recommended to reduce the starting dose in patients with severe renal impairment or ESRD requiring dialysis. Caution should be exercised when ixazomib is administered to patients with severe renal impairment. Ixazomib is not dialyzable and therefore can be administered without regard to the timing of dialysis

Ninlaro

Generic Name: ixazomib

Brand Name: Ninlaro

Synonyms: n.a.

What is Ninlaro?